L-THP is used primarily for its ability to help reduce feelings of stress, to improve mood status, and sometimes for its ability to reduce sensations of pain. In China, L-THP is used for reducing symptoms of pain and as a muscle-relaxant and is sold under the name Rotundine. L-THP is also a powerful anti-inflammatory compound, meaning that it may help to promote good health.
- L-tetrahydropalmatine reduces nicotine self-administration and reinstatement in rats, thereby indicating powerful anti-addiction properties (1).
- Four weeks of l-THP treatment significantly ameliorated the severity of PAWS—specifically, somatic syndrome, mood states, insomnia, and drug craving, in comparison to a placebo group, in terms of drug addiction (2).
- L-Tetrahydropalmatine reduces the development of anxiety and depression-related symptoms induced by single prolonged stress (3).
- L-THP exerts anxiolytic effects via potential interaction with the benzodiazepine binding site on the gamma-aminobutyric acid (GABAA) receptor (4).
- L-THP exerts a prominent anti-inflammatory agent induced by lipopolysaccharide (5).
- L-THP has been used for the treatment of headache and other mild pain. However, little is known about its analgesic effect on chronic pain and its mechanism. It was reported that L-THP exerts remarkable antihyperalgesic effects on neuropathic and inflammatory pain in animal models (6).
- L-THP has been reported to attenuate PTSD-induced changes in gene expression, such as those involving DA, serotonin, and acetylcholine, in the amygdala and hippocampus (7).
- L-THP works as a powerful cardio-protective supplement, helping to prevent damage to the heart under a variety of stresses (8).
How to use
Take one capule, 30-60 minutes before sleep
Need to find the right dose for you? Consider coaching.
This produt deliers very rapid effects. Best cycled.
Stressed individuals, Sleep, Overexcitation.
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Before listing products, we compile a list of available research, to determine if claims match the evidence. Likewise, we scour the the internet to gauge people’s experience with each product. Most of the products listed typically score at least [4.5/5 from reviews]. All the studies we’ve found are listed at the bottom of the page, under citations.
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Medication interactions and allergies
Please consult your healthcare professional before making any changes to your lifestyle or regime.
For further information on contraindications and allergies, please visit the vendors website.
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L-THP acts as a unique way to quieten the mind, improve sleep efficiency and overall calmness. This is very potent and fast acting.
This formuia encompasses a wide range of anxiolytics and sedatives that induce a very profound deep sleep. No tolerance noticed.