THIAMAX - TTFD (Thiamine Tetrahydrofurfuryl Disulfide) Capsules

"The Energy Boosting B-Vitamin"
Thiamine tetrahydrofurfuryl disulfide (TTFD) is the synthetic counterpart of allithiamine, occurring naturally in garlic. Thiamax contains thiamine tetrahydrofurfuryl disulfide, a derivative of thiamine (vitamin B1) with high bioavailability. This form has been shown to cross the blood-brain-barrier and can bypass normal routes of thiamine absorption, with a higher rate of uptake both in the gut and at the cellular level.
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This product is not approved by the TGA and is only suitable for US customers and other approved countries.
How to use


Unlike other forms of thiamine supplementation, TTFD’s molecular structure allows it to pass through intestinal and cellular membranes without the requirement for a transport system. Once inside the cell, it can be activated and used as a cofactor in important biochemical processes. TTFD also has a demonstrated capacity to penetrate the blood brain barrier and increase thiamine levels in the brain and central nervous system, where it may be used to support optimal cognition and maintain autonomic nervous system function. Due to its superior bioavailability, TTFD can be taken in much lower doses than what is considered the “therapeutic dose” of other forms such as thiamine salts.


  • The activity of other enzymes are also influenced by thiamine phosphate esters, where thiamine is not acting as a cofactor but is instead involved in: Allosteric regulation of pyridoxal kinase (enzyme involved in vitamin B6 activation) (4),
  • Thiamine plays a role in the activity of glutamate dehydrogenase (one enzyme responsible for glutamate clearance to reduce neuroexcitoxicity) (5)
  • Allosteric activation of malate dehydrogenase (a mitochondrial enzyme involved in ATP synthesis) (6).
  • Although we must be careful of addiction induced by drugs such as , thiamine tetrahydrofurfuryl disulfide (TTFD), a popular thiamine derivative, is a potential agent for the activation of d


  • Insufficient thiamine can downregulate key energy producing enzymes and therefore reduce the rate at which cells are able to synthesize energy. A more recent discovery has shown that thiamine is necessary for the alpha-oxidation of phytanic acid and 2- hydroxy straight-chain fatty acids, through the action of an enzyme called HACL-1 & 2 (1).
  • Another thiamine-dependent Krebs cycle enzyme complex is alpha-ketoglutarate dehydrogenase. Located in the mitochondria of the cell, this enzyme is involved in the processing of both glucose and fats for energy, as well as processing amino acids and neurotransmitters (2).
  • Dietary proteins are broken down into amino acids, and one class of amino acids is the branched-chain amino acids (valine, leucine, and isoleucine). The thiamine-dependent enzyme, branched-chain-keto acid dehydrogenase, is required to process and make use of these specific amino acids (3).

How to use

THIAMAX - TTFD (Thiamine Tetrahydrofurfuryl Disulfide) Capsules


Start at half a capsule (50mg) and work your way up to your threshold level.


Start at half a capsule (50mg) and work your way up to your threshold level.

Need to find the right dose for you? Consider coaching.

Dosing strategy:

Best used in cyclical fashion.

Ideal for:

Athletes, Students, Fatigue, Focus.


All vendors are vetted for quality, to ensure they contain the right active ingredients and ratios. Each vendor provides a Certificate of Analysis ℹ️, to ensure accurate dosing, and a product free of contaminants/heavy metals. Further, when brands we work with have been randomly pulled off the shelf and tested by Labdoor, they have tended to score A+ ℹ️.


Before listing products, we compile a list of available research, to determine if claims match the evidence. Likewise, we scour the the internet to gauge people’s experience with each product. Most of the products listed typically score at least [4.5/5 from reviews]. All the studies we’ve found are listed at the bottom of the page, under citations.


All products listed on the BYB website follow screening before listing, to ensure there’s a history of long-term usage without adverse effects. Many products fall under the FDA’s Generally Recognized as Safe (GRAS) guidelines.

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Medication interactions and allergies

Please consult your healthcare professional before making any changes to your lifestyle or regime.

For further information on contraindications and allergies, please visit the vendors website.

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THIAMAX is a high grade quality, TTFD supplement that makes it easy to use. With the above factors taken into consideration, it is important to choose a form of thiamine which can bypass these potential difficulties. And here is where TTFD comes in.


THIAMAX/TTFD is a powerful vitamin to enhance energy, focus and mood. It provides a clean boost in energy and supports metabolic health. I'm a huge fan.

Lucas, BYB founder
DISCLAIMER: This product is not intended to diagnose, treat, cure, or prevent any diseases. These statements have not been evaluated by the Therapeutic Goods Administration (TGA) or Food and Drug Administration (FDA). This product is intended for research purposes only. All product information available on the website is for educational purposes only. Bodily introduction of any kind into humans is done at the person’s own risk, and Boost Your Biology assumes no responsibility for health outcomes, good or bad, that may result from ingestion or use. Use should be supervised by a qualified healthcare professional.