Studies in animals show that 7,8-DHF can aid with brain health in a plethora of ways. It is considered highly protective of the brain against various toxins/stressors in the modern world.
- Prevents neuronal cell death, remarkably even stronger than BDNF itself, which leads us to believe that this may prevent age-related cognitive decline and senescence (5).
- 7,8-Dihydroxyflavone displays vasorelaxing and antihypertensive properties, thereby enhances blood flow, and combats lowers blood pressure (7).
- Demonstrates a strong ability to protect dopamine neurons from cell death, thereby facilitates optimal brain function (6).
- May play a pivotal role in recovery after traumatic brain injury, via TrkB signalling (8).
- May prevent synaptic memory loss and deficits in synaptic plasticity (9).
- 7,8-Dihydroxyflavone improves memory consolidation processes in rats and mice (1).
- 7,8-Dihydroxyflavone induces synapse expression of AMPA GluA1 and ameliorates cognitive and spine abnormalities, thereby exerting a potent protective qualities (2).
- 7,8-Dihydroxyflavone is a BDNF receptor agonist, therefore is beneficial in neurogenesis, neuronal survival, neuroplasticity and resilience to low mood(3).
- 7,8-Dihydroxyflavone promotes neurogenesis and exhibits Potent mood elevating effects (4).
How to use
As a dietary supplement, take 25mg of 7,8 DHF 1-2 times daily. It appears to be subject to extensive first-pass metabolism in the liver. Due to improved bioavailability, sublingual administration (under the tongue) may be preferred.
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Best used in acute situations.
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All vendors are vetted for quality, to ensure they contain the right active ingredients and ratios. Each vendor provides a Certificate of Analysis ℹ️, to ensure accurate dosing, and a product free of contaminants/heavy metals. Further, when brands we work with have been randomly pulled off the shelf and tested by Labdoor, they have tended to score A+ ℹ️.
Before listing products, we compile a list of available research, to determine if claims match the evidence. Likewise, we scour the the internet to gauge people’s experience with each product. Most of the products listed typically score at least [4.5/5 from reviews]. All the studies we’ve found are listed at the bottom of the page, under citations.
All products listed on the BYB website follow screening before listing, to ensure there’s a history of long-term usage without adverse effects. Many products fall under the FDA’s Generally Recognized as Safe (GRAS) guidelines.
Medication interactions and allergies
Please consult your healthcare professional before making any changes to your lifestyle or regime.
For further information on contraindications and allergies, please visit the vendors website.
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7,8 DHF is a very novel and unique compound that upholds a strong status within the nootropic sphere. The modern scientific evidence is revealing very impressive results, for all areas of brain health. This compound is motivating and turns the "lights on", eliminates brain fog and improves memory function.
I am yet to trial 7,8 DHF, although I have heard only positive results. It appears to work rather quickly. Tolerance does build quickly though. Not unlike caffeine.