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Benefits
Methylene Blue is currently being studied as potential therapy for mild cognitive impairment, Alzheimer’s and Parkinson’s disease, and other neurodegenerative disorders. All sharing a common problem with mitochondrial function.
Brain
- Methylene Blue inhibits monoamine oxidase and acetylcholinesterase activity which increases levels of catecholamines and acetylcholine. And boosts serotonin and norepinephrine affecting anxiety, depression and memory (1).
- Methylene Blue assists brain cell respiration by increasing oxygen. And donating electrons to the electron transport chain within mitochondria. This same process is used to feed mitochondrial ATP when you eat. So MB provides this fuel without you having to eat (2).
- Neuroprotectant: Methylene Blue is a potent antioxidant. Reactive oxygen species are produced inside mitochondria. The first free radical that is formed inside a cell is superoxide. MB will bind to superoxide and reduce it to water. It stops the oxidative cascade at its very beginning (3).
- Methylene Blue quickly crosses the blood-brain barrier. It improves mitochondrial efficiency and respiration, acts as an antioxidant, and increases brain cell lifespan. Resulting in improved memory and mood 4).
Longevity
- Alzheimer’s disease and other forms of dementia are associated with a buildup of the protein Tau. Clinical trials show that Methylene Blue inhibits Tau formation. And is under consideration as a treatment for Alzheimer’s (5).
- Methylene Blue boosts neuron resistance to the formation of amyloid plaques and neurofibrillary tangles. And helps repair impairments in mitochondrial function and cellular metabolism (6).
- Research shows that Methylene Blue is an effective anti-aging nootropic. MB increases mitochondrial complex IV by 30%, enhances cellular oxygen consumption by 37-70%, increases heme synthesis, and reverses premature senescence caused by H2O2 or cadmium (7).
How to use
Methylene Blue (Supplement)
0.5mg-5mg***
N/A
Need to find the right dose for you? Consider coaching.
Dosing strategy:
Best used every other day. Not consecutively.
Ideal for:
Students, Athletes, Studying, Longevity, Health.
Quality
All vendors are vetted for quality, to ensure they contain the right active ingredients and ratios. Each vendor provides a Certificate of Analysis ℹ️, to ensure accurate dosing, and a product free of contaminants/heavy metals. Further, when brands we work with have been randomly pulled off the shelf and tested by Labdoor, they have tended to score A+ ℹ️.
Efficacy
Before listing products, we compile a list of available research, to determine if claims match the evidence. Likewise, we scour the the internet to gauge people’s experience with each product. Most of the products listed typically score at least [4.5/5 from reviews]. All the studies we’ve found are listed at the bottom of the page, under citations.
Safety
All products listed on the BYB website follow screening before listing, to ensure there’s a history of long-term usage without adverse effects. Many products fall under the FDA’s Generally Recognized as Safe (GRAS) guidelines.
Medication interactions and allergies
Please consult your healthcare professional before making any changes to your lifestyle or regime.
For further information on contraindications and allergies, please visit the vendors website.
Buy from a BYB
Many neurohackers report the biggest nootropic effect they experience with Methylene Blue is “after the fact learning”. You take in the information. And it’s like your brain sorts through the material. Then stores it in a form you can easily access later. Methylene Blue has this uncanny ability to rewire your brain to forget about any negative associations you have of a situation. And only retains the positive aspects of that memory.
Methylene blue enhances my reading speed and comprehension abilities. It seems to help me get into a flow state much easier too. I like how it makes me function at a very low dose (50-100mcg).
