JBSNF-000088 Capsule Blend (Fat Loss)

"Body Composition Hack Blend"
JBSNF-000088 inhibits NNMT activity, reduces MNA levels and drives insulin sensitization, glucose modulation and body weight reduction in animal models of metabolic disease. In mice with high fat diet (HFD)-induced obesity, JBSNF-000088 caused a reduction in body weight, improved insulin sensitivity and normalized glucose tolerance to the level of lean control mice.

NMN (Nicotinamide N-methyltransferase) is an enzyme critical to the metabolism of NAD and thus a key player in metabolic regulation. Research has shown NMN to decrease age-associated body weight gain, improve energy metabolism, improved insulin sensitivity and plasma lipid profile, enhanced eye function and other pathophysiology's. These three compounds affect everything from energy metabolism to cellular performance to aging, primarily by affecting levels of NAD, the expression of GLUT-4 receptors, the activity of the NNMT enzyme, and the production of molecules known as sirtuins. By increasing levels of NAD and decreasing the activity of NNMT, these molecules work together to improve cellular metabolism, enhance weight loss, and improve glucose control. Further benefits of the synergy between these peptides are seen in cellular aging, where increased levels of NAD help stem cells to survive and thrive. This provides a pool of healthy cells that can readily take the place of those that are worn or damaged, leading to improved tissue function and decreased effects of aging. By combining these three peptides, it might be possible to drastically alter energy metabolism for the better while simultaneously boosting anti-aging, anti-inflammatory, and anti-apoptosis activity in cells.

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Benefits
How to use
Evidence

Benefits

These compounds affect everything from energy metabolism to cellular performance to aging, primarily by affecting levels of NAD, the expression of GLUT-4 receptors, the activity of the NNMT enzyme, and the production of molecules known as sirutins. By increasing levels of NAD and decreasing the activity of NNMT, these molecules work together to improve cellular metabolism, enhance weight loss, and improve glucose control. The latter is further enhanced by the fact that NNMT inhibition boosts the expression of GLUT-4 receptors, insulin-independent glucose transporters that are linked to decreased risk of diabetes and improved insulin sensitivity. Further benefits of the synergy between these peptides are seen in cellular aging, where increased levels of NAD help stem cells to survive and thrive. This, of course, provides a pool of healthy cells that can readily take the place of those that are worn or damaged, leading to improved tissue function and decreased effects of aging. These anti-aging effects also lead to performance gains as the combination of these molecules helps to ensure that tissue and organ systems are composed of the healthiest, most active cells available.

Fat Loss

  • Each of these peptides has a positive impact of energy metabolism. NMN, for instance, boosts NAD levels. Low NAD has long been associated with obesity while high NAD is generally associated with healthy diets rich in vegetables. High levels of NAD are associated with ideal body mass composition and increased longevity. High NAD levels will definitely increase energy metabolism and lower obesity (1).
  • All three of these compounds can help to reduce the risk of diabetes. JBSNF-000088 is the most potent anti-diabetic in this group and has been shown in mouse models to drastically improve glucose handling, even in genetically obese mice (1).
  • Like JBSNF-000088, 5 amino-1MQ helps to regulate blood sugar levels by decreasing activity of NNMT. In this case, the research indicates that 5-amino-1MQ increases the transport of glucose by boosting GLUT-4 expression (1).
  • NAD is a primary marker of aging, declining over time and in certain disease conditions. NMN enhances NAD biosynthesis. In mouse models, NMN administration has been shown to mitigate age-related physiological decline without any side effects (1).

Longevity

  • Like JBSNF-000088, 5 amino-1MQ helps to regulate blood sugar levels by decreasing activity of NNMT. In this case, the research indicates that 5-amino-1MQ increases the transport of glucose by boosting GLUT-4 expression.
  • Research shows that NMN, which can reduce adiposity and improving mitochondrial function, may also protect beta cells in the pancreas from damage. This benefit has been shown in both Type I and Type II diabetes.
  • JBSNF-000088 and 5-amino-1MQ work to move sugar from the blood and into cells where it can be used. This improves insulin sensitivity because the GLUT-4 transporter works independently of insulin. Thus, glucose levels drop even as insulin levels remain the same. This takes pressure off the pancreas and helps to prevent “insulin burnout.”
  • Adding to the performance gains of an increased supply of stem cells in NMN, which boosts NAD levels and thus helps to maintain normal metabolic function. This means that existing cells can continue to perform at their peak because they have access to the energy they need. For NMN, this has been most clearly demonstrated in brain tissue.

How to use

JBSNF-000088 Capsule Blend (Fat Loss)

Dosage

Take 1 capsule in the morning and 1 capsule at lunch.

Serving

5-Amino-1mq 50mg, JBSNF-000088 5mg, NMN 50mg

Need to find the right dose for you? Consider coaching.

Dosing strategy:

Best used in 6 week cycles.

Ideal for:

This product is designed to support the following: Weight Loss, Energy Metabolism, Diabetes, Blood Sugar, Anti-Aging, Performance, Muscle Protection.

Quality

All vendors are vetted for quality, to ensure they contain the right active ingredients and ratios. Each vendor provides a Certificate of Analysis ℹ️, to ensure accurate dosing, and a product free of contaminants/heavy metals. Further, when brands we work with have been randomly pulled off the shelf and tested by Labdoor, they have tended to score A+ ℹ️.

Efficacy

Before listing products, we compile a list of available research, to determine if claims match the evidence. Likewise, we scour the the internet to gauge people’s experience with each product. Most of the products listed typically score at least [4.5/5 from reviews]. All the studies we’ve found are listed at the bottom of the page, under citations.

Safety

All products listed on the BYB website follow screening before listing, to ensure there’s a history of long-term usage without adverse effects. Many products fall under the FDA’s Generally Recognized as Safe (GRAS) guidelines.

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Medication interactions and allergies

Please consult your healthcare professional before making any changes to your lifestyle or regime.

For further information on contraindications and allergies, please visit the vendors website.

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These compounds affect everything from energy metabolism to cellular performance to aging, primarily by affecting levels of NAD, the expression of GLUT-4 receptors, the activity of the NNMT enzyme, and the production of molecules known as sirutins. By increasing levels of NAD and decreasing the activity of NNMT, these molecules work together to improve cellular metabolism, enhance weight loss, and improve glucose control.

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This blend is powerful for improving body composition and metabolic health. You heard it here first.

Lucas, BYB founder