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Benefits
A. muciniphila is a recent discovery, but still a pretty cool bacterium with massive potential. It’s found throughout your gastrointestinal tract, particularly in the large intestine. It’s associated with lean individuals, and for that reason is believed to have roles in preventing the development of metabolic disease.
Gut Health
- Akkermansia doesn’t deplete the mucus layer by eating it. Quite the opposite: they actually encourage the cells there to make even more, strengthening the layer further and giving us—their hosts—all the health benefits that come with having a tough gut barrier (1).
- Produces short chain fatty acids (SCFAs), an energy source for other gut bacteria (2).
- When Akkermansia breaks down mucins, it turns them into short-chain fatty acids (SCFAs), including acetate, which your gut lining cells love Acetate is used by other beneficial bacteria like Faecalibacterium prausnitzii, to make butyrate, which is an essential energy source for the cells lining your gut. This kind of process is called cross-feeding (3).
Insulin Sensitivity
- its abundance suggests improved metabolic disorders, such as metabolic endotoxemia, adiposity insulin resistance and glucose tolerance. The role of A. muciniphila is implicated in declining aortic lesions and atherosclerosis (4)
- The supplementation with A. muciniphila is sufficient to protect mice against high sucrose-induced impairment of glucose intolerance by decreasing βCDCA and increasing insulin secretion and FGF15/19. Furthermore, βCDCA inhibits insulin secretion and FGF15/19 expression (5).
- After three months of supplementation, A. muciniphila reduced the levels of the relevant blood markers for liver dysfunction and inflammation while the overall gut microbiome structure was unaffected. In conclusion, this proof-of-concept study shows that the intervention was safe and well tolerated and that supplementation with A. muciniphila improves several metabolic parameters (6).
How to use
Akkermansia Muciniphila Probiotic (Insulin Sensitivity)
Take one capsule daily with food for at least 12 weeks
100 million AFU per capsule
Need to find the right dose for you? Consider coaching.
Dosing strategy:
Take one capsule daily with food for at least 12 weeks
Ideal for:
Fat loss, gut health, metaboiic health
Quality
All vendors are vetted for quality, to ensure they contain the right active ingredients and ratios. Each vendor provides a Certificate of Analysis ℹ️, to ensure accurate dosing, and a product free of contaminants/heavy metals. Further, when brands we work with have been randomly pulled off the shelf and tested by Labdoor, they have tended to score A+ ℹ️.
Efficacy
Before listing products, we compile a list of available research, to determine if claims match the evidence. Likewise, we scour the the internet to gauge people’s experience with each product. Most of the products listed typically score at least [4.5/5 from reviews]. All the studies we’ve found are listed at the bottom of the page, under citations.
Safety
All products listed on the BYB website follow screening before listing, to ensure there’s a history of long-term usage without adverse effects. Many products fall under the FDA’s Generally Recognized as Safe (GRAS) guidelines.
Medication interactions and allergies
Please consult your healthcare professional before making any changes to your lifestyle or regime.
For further information on contraindications and allergies, please visit the vendors website.
Buy from a BYB
Pendulum Akkermansia has been linked to helping with improved gut health. Pendulum Akkermansia contains one strain: Akkermansia muciniphila. Pendulum Glucose Control also contains Akkermansia muciniphila and five other beneficial strains that are specialized for managing Type 2 diabetes.
Pendulum Akkermansia holds a patented strain of Akkermansia muciniphila; it serves as one of the unique strains discovered through high-resolution DNA sequencing, unavailable anywhere else.
